Miracle Man of Miracle Drugs
Dr. Yellapragada Subbarow

 
Bibliography - Scientific Papers
 

MISCELLANEOUS B COMPLEX VITAMINS

40. A new bios factor in liver extract. (with B. Alexander) Journal of Biological Chemistry 135 (1940):341-342

41. Choline, pantothenic acid and nicotinic acid as essential growth factors for pneumococcus. (with Leo Rane) Journal of Biological Chemistry 134 (1940):455-456

42. Nutritional requirements of the pneumococcus. 1. Growth factors for types I, II, V, VII, VIII. (with Leo Rane) Journal of Bacteriology 40 (1940):695-704

43. The relation of pantothenic acid and succinic acid to the growth of certain micro-organisms. (with Leo Rane) Journal of Nutrition 21 (1941 Suppl): 17

44. A lactobacillus of cecal origin requiring oleic acid. (with A.R. Whitehill and J.J. Oleson) Archives of Biochemistry 15 (1947):31-37

45. The chemical nature of growth factors required by mosquito larvae. I. Riboflavin and thiamine. (with W. Trager). Biological Bulletin 75 (1938) 75-84

46. The chemical nature of growth factors required by mosquito larvae. 11. Pantothenic acid and vitamin B6. (with W. Trager) Journal of General Physiology 23 (1940): 561-568.

FOLIC ACID

47. Synthesis of a compound identical with the L. casei factor isolated from liver. (Angier, Boothe, Hutchings, Mowat, Semb, Stokstad, SubbaRow, Waller, Cosulich, Fahrenbach, Hultquist, Kuh, Northey, Seeger, Sickels and Smith*) Science 102:227-228. August 31, 1945

48. The structure and synthesis of the liver L. casei factor. (Angier, Boothe, Hutchings, Mowat, Semb, Stokstad, SubbaRow, Waller, Cosulich, Fahrenbach, Hultquist, Kuh, Northey, Seeger, Sickels and Smith) Science 103:667-669. May 31, 1946

Papers to New York Academy of Sciences Conference on May 23, 1946

49. Isolation of the Liver L. casei Factor (Stokstad, Hutchings and SubbaRow) Annals of the New York Academy of Sciences 48 (1946):261-263

50. Isolation of the Fermentation L.casei Factor (Hutchings, Stokstad, Bohonos, Sloane and SubbaRow) Ibid. 265-267

51. Degradation of the Fermentation L. casei Factor. I. (Stokstad, Hutchings, Mowat, Boothe, Waller, Angier, Semb and SubbaRow) Ibid. 269-273. II. (Hutchings, Stokstad, Mowat, Boothe, Waller, Angier, Semb and SubbaRow) Ibid. 273-277

52. Structure and synthesis of the pteridine degradation products of the Fermentation L casei Factor. (Mowat, Boothe, Hutchings, Stokstad, Waller, Angier, Semb, Cosulich and SubbaRow) Ibid. 279-81

53. Synthesis of pteroylglutamic acid (Liver L. casei factor) and pteroic acid. (Waller, Hutchings, Mowat, Stokstad, Boothe, Angier, Semb, SubbaRow, Cosulich, Fahrenbach, Hultquist, Kuh, Northey, Seeger, Sickels and Smith) Ibid. 283-287

54. Synthesis of pteroylglutamic acid (Liver L. casei Factor) and pteroic acid. II. (Hultquist, Kuh, Cosulich, Fahrenbach, Northey, Seeger, Sickels, Smith, Angier, Boothe, Hutchings, Mowat, Semb, Stokstad, SubbaRow and Waller) Ibid. 48 Suppl. (1947) I-VI

55. A chemical method for the determination of pteroylglutamic acid and related compounds. (Hutchings, Stokstad, Boothe, Mowat, Waller, Angier, Semb and SubbaRow) Journal of Biological Chemistry 168 (1947):705-710

More informative contributions to the Journal of the American Chemical Society:

56. The isolation of the Fermentation Lactobacillus casei Factor. (Hutchings, Stokstad, Bohonos, Sloane and SubbaRow) JACS 70 (1948): 1-3

57. The isolation of the Lactobacillus casei Factor from liver (Stokstad, Hutchings and SubbaRow) Ibid:3-5

58. The degradation of the Fermentation L. casei Factor. I. (Stokstad, Hutchings, Mowat, Boothe, Waller, Angier, Semb and SubbaRow) Ibid: 5-9

59. Degradation of the Fermentation L. casei Factor. II. (Hutchings, Stokstad, Mowat, Boothe, Waller, Angier, Semb and SubbaRow) Ibid :10-13

60. The structure of the Liver L. casei Factor. (Mowat, Boothe, Hutchings, Stokstad, Waller, Angier, Semb, Cosulich and SubbaRow). Ibid :14-18

61. Synthesis of pteroylglutamic acid (Liver L. casei Factor) and pteroic acid. I. (Waller, Hutchings, Mowat, Stokstad, Boothe, Angier, Semb, SubbaRow, Cosulich, Fahrenbach, Hultquist, Kuh, Northey, Seeger, Sickels and Smith) Ibid :19-22

62. Synthesis of pteroylglutamic acid (Liver L. casei Factor) and pteroic acid. II. (Hultquist, Kuh, Cosulich, Fahrenbach, Northey, Seeger, Sickels, Smith, Angier, Boothe, Hutchings, Mowat, Semb, Stokstad SubbaRow and Waller) Ibid :23-24

63. Synthesis of pteroylglutamic acid. III. (Angier, Stokstad, Mowat, Hutchings, Boothe, Waller, Semb, SubbaRow, Cosulich, Fahrenbach, Hultquist, Kuh, Northey, Seeger, Sickels and Smith) Ibid: 25-26

64. Synthesis of pteroylglutamic acid. IV. (Boothe, Waller, Stokstad, Hutchings, Mowat, Angier, Semb, SubbaRow, Cosulich, Fahrenbach, Hultquist, Kuh, Northey, Seeger, Sickels and Smith) Ibid :27-28

65. The preparation of 2-amino-4-hydroxy-6-keto-5,5-dichlorodihydropyramidine. (Angier, Mowat, Boothe, Waller, Semb, Hutchings, Stokstand and SubbaRow) Ibid: 1274-1275

66. Pteridine chemistry. I. (Angier, Waller, Boothe. Mowat, Semb, Hutchings, Stokstad and SubbaRow) Ibid :3029-3031

( *Folic Acid scientists: Lederle Laboratories: Drs. Robert B. Angier, Nestor Bohonos, James H. Boothe, Brian L. Hutchings, John H. Mowat, Joseph Semb, Nathan Sloane, E.L.R. Stokstad, Y. SubbaRow and Coy W. Waller. Calco Chemical Division of American Cyanamid Company: Drs. Donna B. Cosulich, Marvin J. Fahrenbach, Martin E. Hultquist, Erwin Kuh, Elmore H. Northey, Doris R. Seeger, Jackson P. Sickels and James M. Smith, Jr.)

CANCER DRUGS

67. Pteroylaspartic acid, an antagonist for pteroylglutamic acid. (Hutchings, Mowat, J.J. Oleson, Stokstad, Boothe, Waller, Angier, Semb and SubbaRow) Journal of Biological Chemistry 170 (1947):323-328

68. Pteroic acid derivatives. I. Pteroyl-alpha-glutamylglutamic acid and pteroyl-alpha, gamma-glutamyl-diglutamic acid. (Mowat, Hutchings, Angier, Stokstad, Boothe, Waller, Semb and SubbaRow) Journal of American Chemical Society 70 (1948):1096-1098

69. Pteroic acid derivatives. II. Pteroyl-gamma-glutamylglutamic acid and pteroyl-gamma-glutamyl-gamma~glutamylglutamic acid. (Boothe, Mowat, Hutchings, Angier, Waller, Stokstad, Semb, A.L. Gazzola, and SubbaRow) Ibid :1099-1102

70. Pteroic acid derivatives. III. Pteroyl-gamma-glutamylglutamic acid and pteroyl-gamma-glutamyl-gamma-glutamylglutamic acid. (Boothe, Semb, Waller, Angier, Mowat, Hutchings, Stokstad and SubbaRow) Ibid: 71 (1949):2304-2308

71. Pteroic acid derivatives. IV. Pteroyl-alpha, gamma-glutamyldiglutamic acid. (Mowat, A.L. Gazzola, Hutchings, Boothe, Waller, Angier, Semb and SubbaRow) Ibid:2308-10

72. Pteroic acid derivatives. V. Pteroyl-alpha-glutamyl-alpha-glutamylglutamic acid, pteroyl-gamma-glutamyl-alpha-glutamylglutamic acid and pteroyl-alpha-glutamyl-gamma- glutamylglutamic acid. (Semb, Boothe, Angier, Waller, Mowat, Hutchings and SubbaRow) Ibid:2310-2315

73. Pteroic acid derivatives. VI. Unequivocal syntheses of some isomeric glutamic acid peptides. (Angier, Waller, Hutchings, Boothe, Mowat, Semb and SubbaRow) Ibid: 72 (1950):74-77

74. Synthesis of pteroyl-gamma-glutamyl-gamma-glutamylglutamic acid (teropterin). (Boothe, Mowat, Hutchings, Angier, Waller, Stokstad, Semb, A.L. Gazzola and SubbaRow) Transactions of the New York Academy of Sciences. Series II 10 (Jan. 1948): 70-71

75. The effect of folic acid and its antagonists on Rous chicken sarcoma. (with Paul Little, A. Sampath, V. Paganelli, and E. Locke) Ibid: 91-98

76. Effect of nutrition on tumor response in Rous chicken sarcoma. (with Paul Little and J.J. Oleson) Journal of Laboratory and Clinical Medicine 33 (1948):1139-1143

77. Use of antagonists of pteroylglutamic acid in controlling Rous chicken sarcoma. (with Paul Little and A.Sampath) Ibid: 1144-1149

78. Synthesis and some biological properties of 4-aminopteroylaspartic acid. (Hutchings, Mowat, J.J. Oleson, A.L. Gazzola, E.M. Boggiano, Seeger, Boothe, Waller, Angier, Semb and SubbaRow) Journal of Biological Chemistry 180 (1949):857-863

79. Studies on the inhibitory nature of 4-aminopteroylglutamic acid. (with J.J. Oleson and B.L. Hutchings) Ibid : 175 (1948): 359-365

80. Growth inhibition by substances in liver. (with A.M. Brues, E.B. Jackson and J.C. Aub) Journal of Experimental Medicine 71 (1940):423-438

HETRAZAN

81. Experimental chemotherapy of filariasis. I. Experimental methods for testing drugs against naturally acquired filarial infections in cotton rats and dogs. (with R.I. Hewitt, W.S. Wallace, and

E. White) Journal of Laboratory and Clinical Medicine 32 (1947):1293-1303

82. Experimental chemotherapy of filariasis. II. Effect of piperazine derivatives against naturally acquired filarial infections in cotton rats and dogs. (with R.I. Hewitt, E. White, W.S. Wallace,

H.W. Stewart an d S. Kushner) Ibid : 1304-1313

83. Experimental chemotherapy of filariasis. III. Effect of 1-diethyl-carbamyl-4-methylpiperazine hydrochloride against naturally acquired filarial infections in cotton rats and dogs. (with R.I. Hewitt, S. Kushner, H.W. Stewart, E. White and W.S. Wallace) Ibid:1314-1329

84. Experimental chemotherapy of filariasis. IV. The preparation of derivatives of piperazine. (with H.W. Stewart, R.J. Turner, J.J. Denton, S. Kushner, L.M. Brancone, W.L. McEwen, and R.I. Hewitt) Journal of Organic Chemistry 13 (1948):134-143

85. Experimental chemotherapy of filariasis. V. The preparation of derivatives of piperazine. (with S. Kushner, L.M. Brancone, R.I. Hewitt, W.L. McEwen, H.W. Stewart, R.J. Turner and J.J. Denton) Ibid: 13 (1948):144-153

86. Studies on the chemotherapy of filariasis. VI. Some pharmaco-dynamic properties of 1-diethylcarbamyl-4-methylpiperazine hydrochloride, Hetrazan. (with B.K. Harned, Raymond W. Cunningham, Sybella Halliday, R.E. Vessey, N.N. Yuda, Mary C. Clark, Carolyn H. Hine and Rachel Cosgrove) Journal of Laboratory and Clinical Medicine 33 (1948):216-235

87. The treatment of ascariasis in dogs with 1-diethylcarbamyl-4-methyl-piperazine hydrochloride. (with R. Hewitt, W. Wallace and E. White) Journal of Parasitology 34 (1948):237-239

98. The chemistry of piperazine compounds in the chemotherapy of filariasis. (with S. Kushner, L.M. Brancone, R.I. Hewitt, W.L. McEwen, H.W. Stewart, R.J. Turner and J.J. Denton) Annals of the New York Academy of Sciences 50 (1948):120-127

89. Parasitology of piperazines in the treatment of filariasis. (with R.I. Hewitt, D.E. White, S. Kushner, W.S. Wallace, and H.W. Stewart) Ibid :128-140

90. Some toxicological and pharmacological properties of 1-diethylcarbamyl-4-methylpiperazine hydrochloride, Hetrazan (with B.K. Harned, R.W. Cunningham, Sybella Halliday, R.E. Vessey, N.N. Yuda and Mary C. Clark) Ibid :141-160

POLYMYXIN

91. Chemical studies of polymyxin: Comparison with "Aerosporin" (with P.H. Bell et al of Stamford; and A.C. Dornbush. and S. Kushner of Lederle) Annals of the New York Academy of Sciences 51 (1949):897-908

AUREOMYCIN

92. The Pharmacology of Duomycin. (with B.K. Harned, R.W. Cun­ningharn, M.C. Clark, R. Cosgrove, C.H. Hine, W.J. McCauley, E. Stokey, R.E. Vessey and N.N. Yuda) Annals of the New York Academy of Sciences 51 (1948):182-210

DARVISUL

93. An effective antiviral synthetic. (with M. Sanders and R.C. Alexander) Texas Reports on Biology and Medicine 6 (1948):385-395

94. N-heterocyclic benzene sulfonamides. (with Martin E. Hultquist, Richard P. Germann, John S. Webb, William B. Wright Jr. Barbara Roth and James M. Smith Jr.) Journal of the American Chemical Society 73 (1951):2558-2566

95. U.S. Patent Office, 2,525,319 : Hydroxysulfonamidothiazoles and preparation of the same. (with Martin E. Hultquist)

96. U.S. Patent Office 2,535,635 . Substituted pyrimidines and preparation of the same. (with Martin E. Hultquist)

97. The Patent Office, London 662,798 : Improvements in or relation to the production of Sulphonamides and Intermediates thereof. (with Martin E. Hultquist)

STEROIDS

98. Steroids and the stiffness syndrome in guinea pigs. (with J.J. Oleson, Evelyn C. Van Donk, S. Bernstein and Louis Dorfman) Journal of Biological Chemistry 171 (1947):1-7

99. 7-dehydrocholesteryl chloride and bromide (with S. Bernstein, K.J. Sax) Journal of Organic Chemistry 13 (1948):837-842

100. 7-dehydrocholesterol. (with S. Bernstein, L.J. Binovi, L. Dorfrnan and K.J. Sax) Journal of Organic Chemistry 14 (1949):433-446

TUBERCULOSIS

101. Experimental chemotherapy of tuberculosis. I. Substituted nicotinamides. (with S. Kushner, Harry Dalalian, Robert T. Cassell,. J.L. Sanjurjo and D. McKenzie) Journal of Organic Chemistry 13 (1948):834-836

102. The effect of nicotinic acid amide on experimental tuberculosis of white mice (with D. McKenzie, L. Malone, S. Kushner, and J.J. Oleson) Journal of Laboratory and Clinical Medicine 33 (1948):1249-1253

TRYPANOSOMIASIS

103. Experimental chemotherapy of trypanosomiasis. I. Effect of p-phenylene diguanidine and related compounds against experimental infections with Trypanosoma equiperdum. (with R.I. Hewitt, A. Gumble, S. Kushner, S.R. Safir and, L.M. Brancone) Journal of Pharmacology and Experimental Therapeutics 96 (1949):305-314

104. Experimental chemotherapy of trypanosomiasis. II. The preparation of compounds related to p-phenylene diguanidine. (with S.R. Safir, S. Kushner and L.M. Brancone) Journal of Organic Chemistry 13 (1948):924-932

105. A practical liquid medium for cultivation of Trypanosoma cruzi in large volumes. (with Paul A. Little) Journal of Bacteriology 50 (1945):57-60

BLOOD PRESSURE

106. A new method for the indirect measurement of blood pressure in the rat. (with H. Kersten, W.G. Brosene Jr., and F. Ablondi) Journal of Laboratory and Clinical Medicine 32 (1947):1090-1098

107. Comparison of blood pressure measurements in the rat as obtained by use of the tail and foot methods and by direct femoral puncture. (with F. Ablondi, L. Lipchuck and G.Personeus) Ibid: 1099-1106

MISCELLANEOUS BACTERIOLOGICAL STUDIES

108. Use of refined serum albumin as a nutrient for T. pallidum (with P.A. Little) Journal of Immunology 50 (1945):213-219

109. The use of synthetic medium as an in vitro test of possible chemotherapeutic agents against gram-negative bacteria. (with D. McKenzie, Marilyn Stadler, Jane Boothe, J.J. Oleson) Ibid: 60 (1948) 283-294.

110. Comparison of mouse-protective tests and chick-protective tests of over 600 chemicals against Pasteurella multocida. (with P.A. Little, G. DeMello, and J. Tanjola) Ibid :295-298

111. The mouse-protective test as a means of determining the inhibitory effect of chemicals on Vibrio cholera (with P.A. Little) Ibid :299-302